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Multi-omics integration reveals gut microbiota dysbiosis and metabolic alterations of cerebrospinal fluid in children with epilepsy

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CRC-infiltrating Th17 cells induced the expression of G-CSF by CAF leading to the recruitment to the TME of CD11b + Gr1 + myeloid cells endowed with pro-angiogenic features, and thus promoting resistance to VEGF blockade therapy (137)